Pseudomonas Aeruginosa Treatment

Itchy legs can be uniquely annoying, especially in the cold and dry winter months. And while it's perfect weather for wearing long pants or tights, you might further trigger a need to scratch your itch (especially if the fabric itself is itch-inducing). Plus, you might have a harder time reaching said itch in the first place if the source of your stress is focused more on your calves or around your ankles. While your itchy legs may have you itching for a cure, you need to determine why your legs are bothersome before you can treat the condition. And frustratingly, it can take a dermatologist a while to ID the source of itchy legs as any number of underlying conditions could be to blame, says Alix J. Charles, M.D. , a board-certified dermatologist and fellow of the American Academy of Dermatology (AAD). Meet the Experts: Brendan Camp, M.D. , board-certified dermatologist at MDCS Dermatology; Alix J. Charles, M.D. , a board-certified dermatologist and fellow of the American Academy...

CHAMPAIGN, Ill. — Researchers report in the journal Nature that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa , a bacterium that – once it infects a person – is notoriously difficult to treat.  By bombarding P. aeruginosa with hundreds of compounds and using machine learning to determine the physical and chemical traits of those molecules that accumulated inside it, the team discovered how to penetrate the bacterium's defenses. They used this information to convert an antibacterial drug that previously had no activity against P. aeruginosa into one that did. " Pseudomonas is still the most difficult to treat gram-negative infection, and gram-negative infections are very challenging to treat in general," said University of Illinois Urbana-Champaign chemistry professor Paul Hergenrother, who led the work with former graduate student Emily Geddes, a handful of other grad...

Disney families and children are now at risk, as a specific Disney guest brought an infectious child to the theme parks. This led to an uproar and tear-apart from hundreds of people online. The Mother responsible for this chaos has now responded to the allegations set forth by her content. Credit: Disney Disney Families and Children at Risk After Mother Brings Infectious Child to Parks, Responds to Heavy Criticism Inside The Magic recently reported that a mother took to social media to share a controversial incident during her visit to Disneyland with her toddler. She recounted how another guest momentarily stole her Stanley Cup after she set it down. Whether the theft was intentional or accidental, the mother expressed her satisfaction in knowing the thief would face consequences, as her sick and contagious toddler had been drinking from the cup all day. The mother's desire for revenge on the cup thief sparked significant backlash online. Many people criticized her for p...

You may have dark spots on your face due to melasma, a skin condition in which patches of brown spots appear on the skin. Those patches—also known as hyperpigmentation, a general term for skin discoloration—tend to appear on the cheeks, chin, forehead, nose, and upper lip. Although the patches may cause concern, melasma isn't dangerous. While it can affect anyone, melasma most commonly occurs in people with dark skin tones. It often appears during pregnancy and is known as chloasma and the "mask of pregnancy." You can treat the condition for cosmetic reasons if you're wondering how to get rid of the dark spots on your face. Sun protection, however, is key to reducing the appearance and preventing melasma. Here's what you need to know. Getty Images With melasma, treatment goals include reducing melanin production and evening out your skin tone. The time it takes to achieve those goals varies, but you may see results within three to 12 mo...

Abstract The aim of this study is to introduce a dental capping agent for the treatment of pulp inflammation (pulpitis). Nanohydroxyapatite with Elaeagnus angustifolia L. extract (nHAEA) loaded with metronidazole (nHAEA@MTZ) was synthesized and evaluated using a lipopolysaccharide (LPS) in vitro model of pulpitis. nHAEA was synthesized through sol–gel method and analyzed using Scanning Electron Microscopy, Transmission Electron Microscopy, and Brunauer Emmett Teller. Inflammation in human dental pulp stem cells (HDPSCs) induced by LPS. A scratch test assessed cell migration, RT PCR measured cytokines levels, and Alizarin red staining quantified odontogenesis. The nHAEA nanorods were 17–23 nm wide and 93–146 nm length, with an average pore diameter of 27/312 nm, and a surface area of 210.89 m 2 /g. MTZ loading content with controlled release, suggesting suitability for therapeutic applications. nHAEA@MTZ did not affect the odontogenic abilities of HD...