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Lupus treatments: Anifrolumab, deucravacitinib deemed effective - Medical News Today

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Share on Pinterest Two drugs have shown promise in the treatment of lupus in clinical trials. Image credit: luza studios/Getty Images. Lupus is an autoimmune disorder that causes a range of symptoms, some of which can be severe. It is more common in females, who account for 90% of cases. Once doctors confirm the diagnosis, they use treatments such as steroids to reduce inflammation, preventing organ damage and reducing flare-ups of symptoms. However, these treatments can have side effects, particularly with long-term use. Now, two drug trials have shown promising results for the treatment of lupus . In a long-term phase 3 trial, anifrolumab, an intravenous monoclonal antibody, and in a phase 2 trial, deucravacitinib, an oral treatment, emerged as both safe and effective. Autoimmune diseases occur when the body's immune system, which defends against disease, starts to attack healthy tissues. There are more than 80 known autoimmune diseases, which can affect almost any part of the b...

Cutaneous Fungal Infections in Patients Experiencing Homelessness and Treatment in Low-Resource Settings: A Scoping Review - Cureus

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Cutaneous fungal infections (CFIs) affect roughly 25% of the world population [1]. In the United States, CFIs comprised approximately 4 million visits to medical providers from 1995 to 2004 [2]. Although many CFIs can follow an indolent course in immunocompetent individuals, they can also predispose patients to epidermal dysfunction and become a nidus for superimposed infections. Patients experiencing homelessness (PEH) form a group particularly vulnerable to CFIs and CFI-related complications such as cellulitis and osteomyelitis [1-3]. This can be attributed to a multitude of causes, including increased rates of traumatic injury, chronic illnesses, malnutrition, and decreased access to reliable healthcare services. PEH often face barriers to adequate care, particularly in the traditional clinic setting. To address some of these barriers, providers have established mobile clinics, which allow for the evaluation of CFIs in a street setting. Limited funding and volunteer-based staffi...

Histoplasmosis Lung Infections Widespread Across the US: Study - Gizmodo

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The fungus histoplasma, which causes lung infections, was concentrated in the Midwest in the 1950s and 60s (top map), but now causes significant disease throughout much of the country (bottom). Graphic: Patrick Mazi and Andrej Spec/Washington University An illness-causing fungus known as histoplasma is in the soil of nearly all U.S. states, a new study suggests. The researchers behind the work say doctors may be relying on outdated risk maps and therefore missing diagnoses of the infections, which can sometimes be deadly. Watch CC Off en A Fleet of Networked Mushroom Farms Is Spreading Across New York  02:28 Now playing Does Beyond Meat's Plant Have a Mold Problem? Tuesday 3:03PM 00:57 Now playing Why Does Shuri See ____ in the Ancestral Plane? Tuesday 10:34AM The CDC claims that his...

Reasons causing an underarm rash and ways to ditch it - MensXP.com

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Sweat, heat, odour and whatnot! The armpits suffer a lot. When it comes to self-care, people usually think of doing manicures, pedicures, facials and spas, but no one talks about underarms. This is a sensitive area of the body which also needs some attention. It might cause itchiness and irritation when not taken properly, leading to fungal infections.  Taking proper care of underarms to prevent odour and itchiness is no uphill climb. Choosing the right products for the armpits and sticking to a routine is an ace in the hole. But, sometimes, choosing the right products and routine is not sufficient; the underarms might need some extra care, especially during summer.  © iStock Just as the body types are different, so are the underlying causes for one's underarm rash. Several itchy armpit types or underarm rashes types depend on different factors. Some might require critical medical attention, and some could be cured easily by a few measure...

Cutaneous Fungal Infections in Patients Experiencing Homelessness and Treatment in Low-Resource Settings: A Scoping Review - Cureus

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Cutaneous fungal infections (CFIs) affect roughly 25% of the world population [1]. In the United States, CFIs comprised approximately 4 million visits to medical providers from 1995 to 2004 [2]. Although many CFIs can follow an indolent course in immunocompetent individuals, they can also predispose patients to epidermal dysfunction and become a nidus for superimposed infections. Patients experiencing homelessness (PEH) form a group particularly vulnerable to CFIs and CFI-related complications such as cellulitis and osteomyelitis [1-3]. This can be attributed to a multitude of causes, including increased rates of traumatic injury, chronic illnesses, malnutrition, and decreased access to reliable healthcare services. PEH often face barriers to adequate care, particularly in the traditional clinic setting. To address some of these barriers, providers have established mobile clinics, which allow for the evaluation of CFIs in a street setting. Limited funding and volunteer-based staffi...