Scientists Use Synthesized Antibiotic to Treat Bacterial Infection in Mice for the First Time - Interesting Engineering

Now for the first time since the antibiotics discovery, scientists have synthesized the drug and used it to treat a bacterial infection. 

Researchers from the University of Lincoln, UK, used a simplified, synthesis form of teixobactin to treat a bacterial infection in mice.

Antibiotic also reduced infection severity

In addition to clearing the infection, the synthesized teixobactin also managed to minimize the severity of the infection which was not achieved by the clinically-used antibiotic, moxifloxacin, used as a control in the study.

The complete findings have been published in the Journal of Medicinal Chemistry. 

There are increasing instances of drug-resistant infections causing fatalities around the globe. The development of new antibiotics is a crucial area of interest for the medical research community. 

Dr Ishwar Singh, a specialist in novel drug design and development from the University of Lincoln's School of Pharmacy, said: "Translating our success with these simplified synthetic versions from test tubes to real cases is a quantum jump in the development of new antibiotics, and brings us closer to realising the therapeutic potential of simplified teixobactin." 

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