Pseudomonas Aeruginosa Treatment

Risankizumab is safe and effective for the long-term treatment of moderate-to-severe plaque psoriasis, according to study findings published in the Journal of the European Academy & Venereology . Researchers previously demonstrated the efficacy and safety of risankizumab for the treatment of moderate to severe plaque psoriasis over a 52-week period in 2 phase 3 UltiMMa-1/2 studies (ClinicalTrials.gov identifier: NCT02684370/ NCT02684357). However, data regarding the efficacy of risankizumab beyond 52 weeks are limited. Therefore, researchers conducted a phase 3 open-label extension study (LIMMitless; ClinicalTrials.gov identifier: NCT03047395) to evaluate the long-term efficacy of risankizumab for the treatment of psoriasis and its disease manifestation subtypes: nail, scalp, and palmoplantar psoriasis. Included patients (N=525) completed the UltiMMa-1/2 studies and subsequently enrolled in the LIMMitless study. Adults with moderate to severe plaque psoriasis we...

[unable to retrieve full-text content] Alkali-thermal humification treatment for simultaneous plant-growth-promoting compounds production and antibiotic ...    ScienceDirect.com

A treatment-resistant, highly contagious form of the skin infection tinea, better known as ringworm, has been reported in the U.S. for the first time, the Centers for Disease Control and Prevention said Thursday. The cases were identified in two patients in New York City.  Ringworm is a common, superficial infection of the skin, hair or nails that is very contagious. It is caused by fungi and is typically treated with antifungal medications, but over the past decade, a treatment-resistant strain has emerged in South Asia. The CDC refers to that increase as "an epidemic." Those cases are specifically referred to as   Tinea indotineae  infections.  These infections, the CDC said, are characterized by "widespread, inflamed, pruritic plaques," or rashes with lesions. The rashes can appear on the body, the thigh, the crease of the thigh, the pubic region and the face. This version of the infection does not respond to terbinafine, the f...

Something else to note is that there are different types of dark spots—and they can all show up on the skin in various forms. "They can appear as sunspots, melasma, and post-inflammatory hyperpigmentation, which can result from acne, bug bites, and other skin rashes," says board-certified dermatologist Dr. Marisa Garshick. The different types of dark spots—and why they occur Sunspots or Solar Lentigines: According to Dr. Nosworthy, sunspots are typically developed as a result of prolonged UV exposure. "They are commonly found on areas of the skin that are frequently exposed to the sun, such as the face, hands, shoulders, and arms," she adds. Post-Inflammatory Hyperpigmentation (PIH): This type of discoloration is a result of trauma or inflammation of the skin—and why derms caution us from popping our own pimples. However, PIH can also appear after an eczema or psoriasis flare-up. You will notice that once the skin has healed, any injured area may appear darker tha...

CNN  —  Parents across the US are beginning to face the struggles of a second winter without enough amoxicillin, the most prescribed antibiotic in the country. Liquid formulations of the drug — first-line treatments for children with strep throat, chest and sinus infections, and earaches — are still in short supply, according to the US Food and Drug Administration's drug shortage database. And there's no relief in sight. "It is a problem. Respiratory illness season is coming up, and that's going to be a huge issue," said David Margraf, a pharmaceutical research scientist with the University of Minnesota's Resilient Drug Supply Project. Amoxicillin capsules and tablets have not been affected by the shortage, according to the FDA, but young children o...

Dealing with thick, discolored toenails - Harvard Health Headaches are very common in children and teens. We don't tend to think about children getting migraines, but by age 10 one in 20 children has had one. Symptoms may differ from adults and it's important for parents to understand triggers, helpful treatments, and possible red flags. \n ","content":" \n \n \n Headaches are very common in children and teens. In fact, more than half will suffer from headaches at some point, and by 18 years the majority of adolescents have had them. And while most headaches are part of a viral illness, some a...

Abstract Cephalosporins comprise a β-lactam antibiotic class whose first members were discovered in 1945 from the fungus Cephalosporium acremonium . Their clinical use for Gram-negative bacterial infections is widespread due to their ability to traverse outer membranes through porins to gain access to the periplasm and disrupt peptidoglycan synthesis. More recent members of the cephalosporin class are administered as last resort treatments for complicated urinary tract infections, MRSA, and other multi-drug resistant pathogens, such as Neisseria gonorrhoeae . Unfortunately, there has been a global increase in cephalosporin-resistant strains, heteroresistance to this drug class has been a topic of increasing concern, and tolerance and persistence are recognized as potential causes of cephalosporin treatment failure. In this review, we summarize the cephalosporin antibiotic class from discovery to their mechanisms of action, and discuss the causes of cephalosporin treatment failure, whic...